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anti erbb2 monoclonal antibody  (OriGene)


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    Structured Review

    OriGene anti erbb2 monoclonal antibody
    Analysis of the membrane expression of ErbB1, <t>ErbB2,</t> ErbB3, and ErbB4 molecules in FA-proficient and FA-deficient HNSCC cell lines Left and right axes represent, respectively, the percentage of ErbB positive cells and the specific fluorescence intensity (SFI) corresponding to each ErbB receptor. (A) FA-proficient HNSCCs cell lines. (B) FA-deficient HNSCCs cell lines. SFI expression levels of the different ErbB members were obtained as the ratio between the mean fluorescence intensity (MFI) after staining with the corresponding monoclonal antibody (MoAb) relative to MFI obtained with the control isotype. Bars show the mean ± SEM ( n = 3). (C) Representative flow cytometry analysis of ErbB1-ErbB4 receptors in HNSCCs (VU-1131). FA-A and FA-C represent FA complementation groups with mutations in FANCA and FANCC, respectively.
    Anti Erbb2 Monoclonal Antibody, supplied by OriGene, used in various techniques. Bioz Stars score: 93/100, based on 9 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti erbb2 monoclonal antibody/product/OriGene
    Average 93 stars, based on 9 article reviews
    anti erbb2 monoclonal antibody - by Bioz Stars, 2026-06
    93/100 stars

    Images

    1) Product Images from "Lentiviral-mediated panErbB CAR-T cell therapy against head and neck squamous cell carcinomas for patients with Fanconi anemia"

    Article Title: Lentiviral-mediated panErbB CAR-T cell therapy against head and neck squamous cell carcinomas for patients with Fanconi anemia

    Journal: Molecular Therapy Oncology

    doi: 10.1016/j.omton.2025.201060

    Analysis of the membrane expression of ErbB1, ErbB2, ErbB3, and ErbB4 molecules in FA-proficient and FA-deficient HNSCC cell lines Left and right axes represent, respectively, the percentage of ErbB positive cells and the specific fluorescence intensity (SFI) corresponding to each ErbB receptor. (A) FA-proficient HNSCCs cell lines. (B) FA-deficient HNSCCs cell lines. SFI expression levels of the different ErbB members were obtained as the ratio between the mean fluorescence intensity (MFI) after staining with the corresponding monoclonal antibody (MoAb) relative to MFI obtained with the control isotype. Bars show the mean ± SEM ( n = 3). (C) Representative flow cytometry analysis of ErbB1-ErbB4 receptors in HNSCCs (VU-1131). FA-A and FA-C represent FA complementation groups with mutations in FANCA and FANCC, respectively.
    Figure Legend Snippet: Analysis of the membrane expression of ErbB1, ErbB2, ErbB3, and ErbB4 molecules in FA-proficient and FA-deficient HNSCC cell lines Left and right axes represent, respectively, the percentage of ErbB positive cells and the specific fluorescence intensity (SFI) corresponding to each ErbB receptor. (A) FA-proficient HNSCCs cell lines. (B) FA-deficient HNSCCs cell lines. SFI expression levels of the different ErbB members were obtained as the ratio between the mean fluorescence intensity (MFI) after staining with the corresponding monoclonal antibody (MoAb) relative to MFI obtained with the control isotype. Bars show the mean ± SEM ( n = 3). (C) Representative flow cytometry analysis of ErbB1-ErbB4 receptors in HNSCCs (VU-1131). FA-A and FA-C represent FA complementation groups with mutations in FANCA and FANCC, respectively.

    Techniques Used: Membrane, Expressing, Fluorescence, Staining, Control, Flow Cytometry



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    Analysis of the membrane expression of ErbB1, <t>ErbB2,</t> ErbB3, and ErbB4 molecules in FA-proficient and FA-deficient HNSCC cell lines Left and right axes represent, respectively, the percentage of ErbB positive cells and the specific fluorescence intensity (SFI) corresponding to each ErbB receptor. (A) FA-proficient HNSCCs cell lines. (B) FA-deficient HNSCCs cell lines. SFI expression levels of the different ErbB members were obtained as the ratio between the mean fluorescence intensity (MFI) after staining with the corresponding monoclonal antibody (MoAb) relative to MFI obtained with the control isotype. Bars show the mean ± SEM ( n = 3). (C) Representative flow cytometry analysis of ErbB1-ErbB4 receptors in HNSCCs (VU-1131). FA-A and FA-C represent FA complementation groups with mutations in FANCA and FANCC, respectively.
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    Image Search Results


    Analysis of the membrane expression of ErbB1, ErbB2, ErbB3, and ErbB4 molecules in FA-proficient and FA-deficient HNSCC cell lines Left and right axes represent, respectively, the percentage of ErbB positive cells and the specific fluorescence intensity (SFI) corresponding to each ErbB receptor. (A) FA-proficient HNSCCs cell lines. (B) FA-deficient HNSCCs cell lines. SFI expression levels of the different ErbB members were obtained as the ratio between the mean fluorescence intensity (MFI) after staining with the corresponding monoclonal antibody (MoAb) relative to MFI obtained with the control isotype. Bars show the mean ± SEM ( n = 3). (C) Representative flow cytometry analysis of ErbB1-ErbB4 receptors in HNSCCs (VU-1131). FA-A and FA-C represent FA complementation groups with mutations in FANCA and FANCC, respectively.

    Journal: Molecular Therapy Oncology

    Article Title: Lentiviral-mediated panErbB CAR-T cell therapy against head and neck squamous cell carcinomas for patients with Fanconi anemia

    doi: 10.1016/j.omton.2025.201060

    Figure Lengend Snippet: Analysis of the membrane expression of ErbB1, ErbB2, ErbB3, and ErbB4 molecules in FA-proficient and FA-deficient HNSCC cell lines Left and right axes represent, respectively, the percentage of ErbB positive cells and the specific fluorescence intensity (SFI) corresponding to each ErbB receptor. (A) FA-proficient HNSCCs cell lines. (B) FA-deficient HNSCCs cell lines. SFI expression levels of the different ErbB members were obtained as the ratio between the mean fluorescence intensity (MFI) after staining with the corresponding monoclonal antibody (MoAb) relative to MFI obtained with the control isotype. Bars show the mean ± SEM ( n = 3). (C) Representative flow cytometry analysis of ErbB1-ErbB4 receptors in HNSCCs (VU-1131). FA-A and FA-C represent FA complementation groups with mutations in FANCA and FANCC, respectively.

    Article Snippet: Primary antibodies used were anti-EGFR monoclonal antibody (no. 4267, Cell Signaling, 1:20) and anti-Erbb2 monoclonal antibody (no. UMAB36, Origene, 1:20).

    Techniques: Membrane, Expressing, Fluorescence, Staining, Control, Flow Cytometry